Lobeline hydrochloride ( Lobeline hydrochloride )

Catalog No. M11393 CAS No. 134-63-4

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Product Name

Lobeline hydrochloride
Note

Research use only, not for human use.
Brief Description

Lobeline hydrochloride, a nicotinic receptor agonist, acting as a potent antagonist at both α3β2 and α4β2 neuronal nicotinic receptor subtypes.
Description

Lobeline hydrochloride, a nicotinic receptor agonist, acting as a potent antagonist at both α3β2 and α4β2 neuronal nicotinic receptor subtypes.
Synonyms

Lobeline hydrochloride
Pathway

Endocrinology/Hormones
Target

AChR
Recptor

nAChR; Nicotinic Receptor
Research Area

Neurological Disease
Indication

——

CAS Number

134-63-4
Formula Weight

273.92
Molecular Formula

C22H27NO2·HCl
Purity

>98%(HPLC)
Solubility

Water: 1g/40mL
SMILES

CN1[C@@H](CC(C2=CC=CC=C2)=O)CCC[C@H]1C[C@H](O)C3=CC=CC=C3.[H]Cl
Chemical Name

2-[(2R,6S)-6-[(2S)-2-Hydroxy-2-phenylethyl]-1-methylpiperidin-2-yl]-1-phenylethanone hydrochloride

1.Meyer AC, et al. J Neurochem. 2013 Oct;127(2):187-98.

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