Lobeline hydrochloride

CAS No. 134-63-4

Lobeline hydrochloride ( Lobeline hydrochloride )

Catalog No. M11393 CAS No. 134-63-4

Lobeline hydrochloride, a nicotinic receptor agonist, acting as a potent antagonist at both α3β2 and α4β2 neuronal nicotinic receptor subtypes.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
50MG 41 In Stock
100MG 74 In Stock
200MG 87 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Lobeline hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Lobeline hydrochloride, a nicotinic receptor agonist, acting as a potent antagonist at both α3β2 and α4β2 neuronal nicotinic receptor subtypes.
  • Description
    Lobeline hydrochloride, a nicotinic receptor agonist, acting as a potent antagonist at both α3β2 and α4β2 neuronal nicotinic receptor subtypes.
  • Synonyms
    Lobeline hydrochloride
  • Pathway
    Endocrinology/Hormones
  • Target
    AChR
  • Recptor
    nAChR; Nicotinic Receptor
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    134-63-4
  • Formula Weight
    273.92
  • Molecular Formula
    C22H27NO2·HCl
  • Purity
    >98%(HPLC)
  • Solubility
    Water: 1g/40mL
  • SMILES
    CN1[C@@H](CC(C2=CC=CC=C2)=O)CCC[C@H]1C[C@H](O)C3=CC=CC=C3.[H]Cl
  • Chemical Name
    2-[(2R,6S)-6-[(2S)-2-Hydroxy-2-phenylethyl]-1-methylpiperidin-2-yl]-1-phenylethanone hydrochloride

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Meyer AC, et al. J Neurochem. 2013 Oct;127(2):187-98.
molnova catalog
related products
  • Dichlorisone Acetate

    It belongs to organophosphate compounds, used as a kind of common environmental health insecticide.

  • PHA 568487

    The quinuclidine PHA 568487 is an agonist of the alpha 7 nicotinic acetylcholine receptor that was designed to mitigate the bioactivation associated with the core scaffold and subsequently remove associated liabilities with in vivo tolerability.

  • Catestatin

    Non-competitive nicotinic cholinergic antagonist; selectively inhibits nicotinic-stimulated catecholamine secretion from chromaffin cells and noradrenergic neurons (IC50 ~ 200 nM). Blocks nicotinic-induced cationic signaling (IC50 ~ 200 - 250 nM) and inhibits nicotinic-agonist induced desensitization of catecholamine release. Also stimulates mast cell release of histamine via a separate mechanism.